YESINTEK™ Copay Assistance and 
IV Savings Program Terms & Conditions

  • With this YESINTEK Copay Assistance Program, eligible patients may Pay As Little As (PALA) $0 for each monthly fill of YESINTEK (ustekinumab-kfce) injection, while this program remains in effect. Subject to all other terms and conditions, this copay assistance program may be used to reduce the amount of an eligible patient’s out-of-pocket costs for YESINTEK up to the full amount of the patient’s out-of-pocket cost per prescription, subject to a maximum aggregate amount while this copay assistance program remains in effect. Whether a patient is eligible to receive the maximum aggregate amount is determined by the type of commercial insurance plan coverage the patient has and may vary among individual patients covered by different plans. Additional information on the program and whether your particular insurance coverage is likely to result in your reaching the maximum aggregate amount can be obtained by calling 1-833-61-BIOCON (1-833-612-4626). Valid prescription is required. No other purchase is necessary. Biocon Biologics reserves the right to amend or end this copay assistance program at any time without notice.
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  • Eligibility Requirements: This copay assistance can be redeemed only by patients age 6 or older and who are residents of the U.S. or Puerto Rico. For patients under the age of 18, authorization is required from legal guardian. Patients must have commercial prescription drug insurance with coverage for YESINTEK. This copay assistance program is not valid for uninsured patients or commercially insured patients without coverage for YESINTEK; not valid for patients who are covered in whole or in part by any state or federally funded healthcare program, including, but not limited to, any state pharmaceutical assistance program, (Medicare Part D or otherwise), Medicaid, Medigap, VA or DOD, or TRICARE (regardless of whether YESINTEK injection is covered by such government program); not valid if the patient is Medicare eligible and enrolled in an employer-sponsored health plan or prescription benefit program for retirees; and not valid if the patient’s insurance plan is paying the entire cost of this prescription. This copay assistance program is void outside the U.S. or Puerto Rico or in any state or jurisdiction where prohibited by law, taxed or restricted. Absent a change in Massachusetts law, this copay assistance program will no longer be valid for Massachusetts residents as of January 1, 2026.
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  • This copay assistance program is not health insurance. The copay assistance program is not transferable, and the amount of the savings cannot exceed the patient’s out-of-pocket costs. Cannot be combined with any other rebate/coupon, cash discount card, free trial, or similar offer for the specified prescription. This copay assistance is not redeemable for cash. This copay assistance is not valid for product dispensed by a 340B covered entity that purchased the product at discounted pricing under the 340B drug pricing program.
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  • The value of this copay assistance program is exclusively for the benefit of patients and is intended to be credited solely towards patient out-of-pocket costs, including applicable co-payments, coinsurance, deductibles and one time administration charges for the IV induction dose up to a maximum of $100. This copay assistance is not available if the patient’s commercial insurance plan, pharmacy benefit manager, or other plan agent uses a copay adjustment program that restricts program payments from being applied to satisfy the patient’s out-of-pocket costs or counted toward the patient’s out-of-pocket maximum limits. This copay assistance program also is not available to patients who are members of insurance plans that adjust, reduce, or waive their patients. Out-of-pocket costs based on the availability of, or a member’s participation in, manufacturer-sponsored copay assistance. These programs are often referred to as accumulator adjustment or maximizer programs. Patients with these plan terms may not use this copay assistance program but may be eligible for other needs-based assistance provided by Biocon Biologics. If you believe your commercial insurance plan may have such terms, please contact 1-833-61-BIOCON (1-833-612-4626). Biocon Biologics, in its sole discretion, may reduce or eliminate program benefits for any patient whose plan requires enrollment in the program as a condition of participation in any plan or plan benefit, coverage, or program or otherwise imposes different or additional requirements on patients who receive this copay assistance.
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NOTICE. Data related to your use of this copay assistance program may be collected, analyzed and shared with Biocon Biologics for market research and other purposes related to assessing its copay assistance programs. Data shared with Biocon Biologics will be aggregated and de-identified, meaning it will be combined with data related to other copay assistance program redemptions and will not identify you.

  • Use of this copay assistance program must be consistent with the terms of any drug benefit provided by a commercial health insurer, health plan or private third-party payer. Patients must have not submitted and will not submit a claim for reimbursement under any federal, state or other governmental programs for this prescription. Patients are responsible for reporting the receipt of copay assistance to any commercial insurer, health plan, or third-party payer who pays for or reimburses any part of the prescription filled, as may be required. Patients should not use this copay assistance program if their health plan prohibits use of manufacturer copay assistance programs. Patients should withdraw from this copay assistance program should they begin to receive prescription benefits from any government funded program by calling 1-833-61-BIOCON (1-833-612-4626).
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  • By utilizing this copay assistance program, you hereby accept and agree to abide by these terms and conditions. Any individual or entity who enrolls or assists in the enrollment of a patient in the copay assistance program represents that the patient meets the eligibility criteria and other requirements described herein. Health plans, specialty pharmacies, pharmacy benefit managers, and vendors or agents of any of the foregoing, are prohibited from enrolling or assisting in the enrollment of patients in this copay assistance program. Further, you agree that you currently meet the eligibility criteria and other requirements described herein every time you use this copay assistance program.

IMPORTANT SAFETY INFORMATION

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YESINTEK is a prescription medicine that affects your immune system. YESINTEK can increase your chance of having serious side effects including:

Serious Infections

YESINTEK may lower the ability of your immune system to fight infections and may increase your risk of infections. Some people have serious infections, which may require hospitalization, including tuberculosis (TB), and infections caused by bacteria, fungi, or viruses. Some people have to be hospitalized for treatment of their infection.

  • Your doctor should check you for TB before starting YESINTEK.
  • If your doctor feels that you are at risk for TB, you may be treated with medicine for TB before you begin treatment with YESINTEK and during treatment with YESINTEK.
  • Your doctor should watch you closely for signs and symptoms of TB while you are being treated with YESINTEK.

You should not start taking YESINTEK if you have any kind of infection unless your doctor says it is okay.

Before starting YESINTEK, tell your doctor if you:

  • think you have an infection or have symptoms of an infection such as:
  • fever, sweats, or chills
  • muscle aches
  • cough
  • shortness of breath
  • blood in phlegm
  • weight loss
  • warm, red, or painful skin or sores on your body
  • diarrhea or stomach pain
  • burning when you urinate or urinate more often than normal
  • feel very tired
  • are being treated for an infection or have any open cuts.
  • get a lot of infections or have infections that keep coming back.
  • have TB or have been in close contact with someone with TB.

After starting YESINTEK, call your doctor right away if you have any symptoms of an infection (see above). These may be signs of infections such as chest infections, or skin infections or shingles that could have serious complications. YESINTEK can make you more likely to get infections or make an infection that you have worse.
People who have a genetic problem where the body does not make any of the proteins interleukin 12 (IL-12) and interleukin 23 (IL-23) are at a higher risk for certain serious infections. These infections can spread throughout the body and cause death. People who take YESINTEK may also be more likely to get these infections.

Cancers: YESINTEK may decrease the activity of your immune system and increase your risk for certain types of cancer. Tell your doctor if you have ever had any type of cancer. Some people who are receiving ustekinumab products and have risk factors for skin cancer developed certain types of skin cancers. During your treatment with YESINTEK, tell your doctor if you have any new skin growths.

Posterior Reversible Encephalopathy Syndrome (PRES): PRES is a rare condition that affects the brain and can cause death. The cause of PRES is not known. If PRES is found early and treated, most people recover. Tell your doctor right away if you have any new or worsening medical problems including headache, seizures, confusion, and vision problems.

Serious Allergic Reactions: Serious allergic reactions can occur with YESINTEK. Stop using YESINTEK and get medical help right away if you have any symptoms of a serious allergic reaction such as: feeling faint, swelling of your face, eyelids, tongue, or throat, chest tightness, or skin rash.

Lung Inflammation: Cases of lung inflammation have happened in some people who receive ustekinumab and may be serious. These lung problems may need to be treated in a hospital. Tell your doctor right away if you develop shortness of breath or a cough that doesn’t go away during treatment with YESINTEK.

Common side effects of YESINTEK include: nasal congestion, sore throat, and runny nose, redness at the injection site, upper respiratory infections, vaginal, yeast infections, fever, urinary tract infections, headache, sinus infection, tiredness, bronchitis, itching, diarrhea, nausea and vomiting, stomach pain. These are not all of the possible side effects with YESINTEK. Tell your doctor about any side effect that you experience. Ask your doctor or pharmacist for more information.

Before you receive YESINTEK, tell your doctor about all of your medical conditions, including if you:

  • have any of the conditions or symptoms listed above for serious infections, cancers, or PRES.
  • ever had an allergic reaction to ustekinumab or any of its ingredients. Ask your doctor if you are not sure.
  • have recently received or are scheduled to receive an immunization (vaccine). People who take YESINTEK should not receive live vaccines. Tell your doctor if anyone in your house needs a live vaccine. The viruses used in some types of live vaccines can spread to people with a weakened immune system and can cause serious problems. You should not receive the BCG vaccine during the one year before receiving YESINTEK or one year after you stop receiving YESINTEK.
  • have any new or changing lesions within psoriasis areas or on normal skin.
  • are receiving or have received allergy shots, especially for serious allergic reactions. Allergy shots may not work as well for you during treatment with YESINTEK. YESINTEK may also increase your risk of having an allergic reaction to an allergy shot.
  • receive or have received phototherapy for your psoriasis.
  • are pregnant or plan to become pregnant. It is not known if YESINTEK can harm your unborn baby. You and your doctor should decide if you will receive YESINTEK.
  • received YESINTEK while you were pregnant. It is important that you tell your baby’s healthcare provider before any vaccinations are given to your baby.
  • are breastfeeding or plan to breastfeed. YESINTEK can pass into your breast milk.
  • talk to your doctor about the best way to feed your baby if you receive YESINTEK.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.

When prescribed YESINTEK:

  • Use YESINTEK exactly as your doctor tells you to.
  • Adults with Crohn’s disease and ulcerative colitis will receive the first dose of YESINTEK through a vein in the arm (intravenous infusion) in a healthcare facility by a healthcare provider. It takes at least 1 hour to receive the full dose of medicine. You will then receive YESINTEK as an injection under the skin (subcutaneous injection) 8 weeks after the first dose of YESINTEK, as described below.
  • Adults with psoriasis or psoriatic arthritis, and children 6 years and older with psoriasis or psoriatic arthritis will receive YESINTEK as an injection under the skin (subcutaneous injection) as described below.

Injecting YESINTEK under your skin:

  • YESINTEK is intended for use under the guidance and supervision of your doctor. In children 6 years and older, it is recommended that YESINTEK be administered by a healthcare provider. If your doctor decides that you or a caregiver may give your injections of YESINTEK at home, you should receive training on the right way to prepare and inject YESINTEK. Your doctor will determine the right dose of YESINTEK for you, the amount for each injection, and how often you should receive it. Do not try to inject YESINTEK yourself until you or your caregiver have been shown how to inject YESINTEK by your doctor or nurse.
  • Inject YESINTEK under the skin (subcutaneous injection) in your upper arms, buttocks, upper legs (thighs) or stomach area (abdomen).
  • Do not give an injection in an area of the skin that is tender, bruised, red or hard.
  • Use a different injection site each time you use YESINTEK.
  • If you inject more YESINTEK than prescribed, call your doctor right away.
  • Be sure to keep all of your scheduled follow-up appointments.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit https://www.fda.gov/medwatch
or call 1-800-FDA-1088.

WHAT IS YESINTEK (ustekinumab-kfce)?

YESINTEK is a prescription medicine used to treat: adults and children 6 years and older with moderate to severe psoriasis who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet light alone or with pills); adults and children 6 years and older with active psoriatic arthritis; adults 18 years and older with moderately to severely active Crohn’s disease; adults 18 years and older with moderately to severely active ulcerative colitis.
It is not known if YESINTEK is safe and effective in children less than 6 years of age.

IMPORTANT SAFETY INFORMATION

YESINTEK is a prescription medicine that affects your immune system. YESINTEK can increase your chance of having serious side effects including:

Serious Infections

YESINTEK may lower the ability of your immune system to fight infections and may increase your risk of infections. Some people have serious infections, which may require hospitalization, including tuberculosis (TB), and infections caused by bacteria, fungi, or viruses. Some people have to be hospitalized for treatment of their infection.

  • Your doctor should check you for TB before starting YESINTEK.
  • If your doctor feels that you are at risk for TB, you may be treated with medicine for TB before you begin treatment with YESINTEK and during treatment with YESINTEK.
  • Your doctor should watch you closely for signs and symptoms of TB while you are being treated with YESINTEK.

You should not start taking YESINTEK if you have any kind of infection unless your doctor says it is okay.

Before starting YESINTEK, tell your doctor if you:

  • think you have an infection or have symptoms of an infection such as:
  • fever, sweats, or chills
  • muscle aches
  • cough
  • shortness of breath
  • blood in phlegm
  • weight loss
  • warm, red, or painful skin or sores on your body
  • diarrhea or stomach pain
  • burning when you urinate or urinate more often than normal
  • feel very tired
  • are being treated for an infection or have any open cuts.
  • get a lot of infections or have infections that keep coming back.
  • have TB or have been in close contact with someone with TB.

After starting YESINTEK, call your doctor right away if you have any symptoms of an infection (see above). These may be signs of infections such as chest infections, or skin infections or shingles that could have serious complications. YESINTEK can make you more likely to get infections or make an infection that you have worse.
People who have a genetic problem where the body does not make any of the proteins interleukin 12 (IL-12) and interleukin 23 (IL-23) are at a higher risk for certain serious infections. These infections can spread throughout the body and cause death. People who take YESINTEK may also be more likely to get these infections.

Cancers: YESINTEK may decrease the activity of your immune system and increase your risk for certain types of cancer. Tell your doctor if you have ever had any type of cancer. Some people who are receiving ustekinumab products and have risk factors for skin cancer developed certain types of skin cancers. During your treatment with YESINTEK, tell your doctor if you have any new skin growths.

Posterior Reversible Encephalopathy Syndrome (PRES): PRES is a rare condition that affects the brain and can cause death. The cause of PRES is not known. If PRES is found early and treated, most people recover. Tell your doctor right away if you have any new or worsening medical problems including headache, seizures, confusion, and vision problems.

Serious Allergic Reactions: Serious allergic reactions can occur with YESINTEK. Stop using YESINTEK and get medical help right away if you have any symptoms of a serious allergic reaction such as: feeling faint, swelling of your face, eyelids, tongue, or throat, chest tightness, or skin rash.

Lung Inflammation: Cases of lung inflammation have happened in some people who receive ustekinumab and may be serious. These lung problems may need to be treated in a hospital. Tell your doctor right away if you develop shortness of breath or a cough that doesn’t go away during treatment with YESINTEK.

Common side effects of YESINTEK include: nasal congestion, sore throat, and runny nose, redness at the injection site, upper respiratory infections, vaginal, yeast infections, fever, urinary tract infections, headache, sinus infection, tiredness, bronchitis, itching, diarrhea, nausea and vomiting, stomach pain. These are not all of the possible side effects with YESINTEK. Tell your doctor about any side effect that you experience. Ask your doctor or pharmacist for more information.

Before you receive YESINTEK, tell your doctor about all of your medical conditions, including if you:

  • have any of the conditions or symptoms listed above for serious infections, cancers, or PRES.
  • ever had an allergic reaction to ustekinumab or any of its ingredients. Ask your doctor if you are not sure.
  • have recently received or are scheduled to receive an immunization (vaccine). People who take YESINTEK should not receive live vaccines. Tell your doctor if anyone in your house needs a live vaccine. The viruses used in some types of live vaccines can spread to people with a weakened immune system and can cause serious problems. You should not receive the BCG vaccine during the one year before receiving YESINTEK or one year after you stop receiving YESINTEK.
  • have any new or changing lesions within psoriasis areas or on normal skin.
  • are receiving or have received allergy shots, especially for serious allergic reactions. Allergy shots may not work as well for you during treatment with YESINTEK. YESINTEK may also increase your risk of having an allergic reaction to an allergy shot.
  • receive or have received phototherapy for your psoriasis.
  • are pregnant or plan to become pregnant. It is not known if YESINTEK can harm your unborn baby. You and your doctor should decide if you will receive YESINTEK.
  • received YESINTEK while you were pregnant. It is important that you tell your baby’s healthcare provider before any vaccinations are given to your baby.
  • are breastfeeding or plan to breastfeed. YESINTEK can pass into your breast milk.
  • talk to your doctor about the best way to feed your baby if you receive YESINTEK.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.

When prescribed YESINTEK:

  • Use YESINTEK exactly as your doctor tells you to.
  • Adults with Crohn’s disease and ulcerative colitis will receive the first dose of YESINTEK through a vein in the arm (intravenous infusion) in a healthcare facility by a healthcare provider. It takes at least 1 hour to receive the full dose of medicine. You will then receive YESINTEK as an injection under the skin (subcutaneous injection) 8 weeks after the first dose of YESINTEK, as described below.
  • Adults with psoriasis or psoriatic arthritis, and children 6 years and older with psoriasis or psoriatic arthritis will receive YESINTEK as an injection under the skin (subcutaneous injection) as described below.

Injecting YESINTEK under your skin:

  • YESINTEK is intended for use under the guidance and supervision of your doctor. In children 6 years and older, it is recommended that YESINTEK be administered by a healthcare provider. If your doctor decides that you or a caregiver may give your injections of YESINTEK at home, you should receive training on the right way to prepare and inject YESINTEK. Your doctor will determine the right dose of YESINTEK for you, the amount for each injection, and how often you should receive it. Do not try to inject YESINTEK yourself until you or your caregiver have been shown how to inject YESINTEK by your doctor or nurse.
  • Inject YESINTEK under the skin (subcutaneous injection) in your upper arms, buttocks, upper legs (thighs) or stomach area (abdomen).
  • Do not give an injection in an area of the skin that is tender, bruised, red or hard.
  • Use a different injection site each time you use YESINTEK.
  • If you inject more YESINTEK than prescribed, call your doctor right away.
  • Be sure to keep all of your scheduled follow-up appointments.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit https://www.fda.gov/medwatch
or call 1-800-FDA-1088.

WHAT IS YESINTEK (ustekinumab-kfce)?

YESINTEK is a prescription medicine used to treat: adults and children 6 years and older with moderate to severe psoriasis who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet light alone or with pills); adults and children 6 years and older with active psoriatic arthritis; adults 18 years and older with moderately to severely active Crohn’s disease; adults 18 years and older with moderately to severely active ulcerative colitis.
It is not known if YESINTEK is safe and effective in children less than 6 years of age.

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You are now leaving www.YESINTEK.com, a Biocon Biologics website. The website you are about to access is not owned or controlled by Biocon Biologics Inc.

Biocon Biologics Inc. assumes no responsibility for and makes no warranties or representation of any kind as to the accuracy, currency, or completeness of any information contained in such third-party website, including any third-party social media or mobile application platform. Inclusion of any third-party link on this website does not imply an endorsement or recommendation by Biocon Biologics, and a link to this website from another website does not imply a relationship between Biocon Biologics and any third party. Your use of any such third-party site or platform is at your own risk and will be governed by such third party’s terms and policies (including its privacy policy). Biocon Biologics shall not be liable for any direct, indirect, consequential, incidental or punitive damages arising out of access to, use of, or inability to use such third-party website, or any errors or omissions in the content thereof.

You are now leaving www.YESINTEK.com, a Biocon Biologics website. The website you are about to access is not owned or controlled by Biocon Biologics Inc.

Biocon Biologics Inc. assumes no responsibility for and makes no warranties or representation of any kind as to the accuracy, currency, or completeness of any information contained in such third-party website, including any third-party social media or mobile application platform. Inclusion of any third-party link on this website does not imply an endorsement or recommendation by Biocon Biologics, and a link to this website from another website does not imply a relationship between Biocon Biologics and any third party. Your use of any such third-party site or platform is at your own risk and will be governed by such third party’s terms and policies (including its privacy policy). Biocon Biologics shall not be liable for any direct, indirect, consequential, incidental or punitive damages arising out of access to, use of, or inability to use such third-party website, or any errors or omissions in the content thereof.

You are now leaving www.YESINTEK.com, a Biocon Biologics website. The website you are about to access is not owned or controlled by Biocon Biologics Inc.

Biocon Biologics Inc. assumes no responsibility for and makes no warranties or representation of any kind as to the accuracy, currency, or completeness of any information contained in such third-party website, including any third-party social media or mobile application platform. Inclusion of any third-party link on this website does not imply an endorsement or recommendation by Biocon Biologics, and a link to this website from another website does not imply a relationship between Biocon Biologics and any third party. Your use of any such third-party site or platform is at your own risk and will be governed by such third party’s terms and policies (including its privacy policy). Biocon Biologics shall not be liable for any direct, indirect, consequential, incidental or punitive damages arising out of access to, use of, or inability to use such third-party website, or any errors or omissions in the content thereof.

The information contained in this section
of the site is intended for US Healthcare
Professionals only. Select “OK” if you are a
US Healthcare Professional.

INDICATIONS

YESINTEK is a prescription medicine used to treat:
  • adults and children 6 years and older with moderate to severe psoriasis who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet light alone or with pills)
  • adults and children 6 years and older with active psoriatic arthritis
  • adults 18 years and older with moderately to severely active Crohn’s disease
  • adults 18 years and older with moderately to severely active ulcerative colitis

INDICATIONS

YESINTEK is a prescription medicine used to treat:

  • adults and children 6 years and older with moderate to severe psoriasis who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet light alone or with pills)
  • adults and children 6 years and older with active psoriatic arthritis
  • adults 18 years and older with moderately to severely active Crohn’s disease
  • adults 18 years and older with moderately to severely active ulcerative colitis